Named reactions index

Diels-Alder cycloaddition

specified-next: not executable as a chemically faithful v2 rule yet because geometry/stereochemistry guards are missing.

Interactive Route Player

Use next/prev to step through the route: first the current state is shown without highlight, then the next ownership move is previewed, then the move is executed. If a route snapshot changes several ownership records, the player unfolds them one at a time. Drag a node to fix it; double-click a fixed node to release it.

HEG v2 State Sketches

These panels are rendered from ownership-structured HEG v2 objects. For specified-next examples they are state sketches, not yet products of executable v2 rules.

Diels-Alder substrate HEG sketch

Diels-Alder substrate HEG sketch

Butadiene plus ethene with explicit pi-pair resources.

Diels-Alder composite snapshot 1

Diels-Alder composite snapshot 1

Composite-rule snapshot: first terminal sigma pair is present. This is not meant as an isolated chemical intermediate.

Diels-Alder composite snapshot 2

Diels-Alder composite snapshot 2

Composite-rule snapshot: both terminal sigma pairs are present before the final pi-shift snapshot.

Diels-Alder route product

Diels-Alder route product

Cyclohexene skeleton: two new sigma pairs and one retained pi pair.

DPO-like Step Panels

Each primitive snapshot is shown as L/K/R. Red marks the ownership edge removed from L, orange marks the halfedge whose owner changes, and green marks the ownership edge created in R. K keeps the common atoms, halfedges, pair objects, and unchanged ownership records. For specified-next examples this is an explanatory span derived from route snapshots, not yet a checked executable rule application.

Diels-Alder composite route step 1

Diels-Alder substrate HEG sketch -> Diels-Alder composite snapshot 1

h11: a5 -> a6; h12: a6 -> a1

L

L panel

K

K panel

R

R panel

Diels-Alder composite route step 2

Diels-Alder composite snapshot 1 -> Diels-Alder composite snapshot 2

h7: a3 -> a4; h8: a4 -> a5

L

L panel

K

K panel

R

R panel

Diels-Alder composite route step 3

Diels-Alder composite snapshot 2 -> Diels-Alder route product

h3: a1 -> a2; h4: a2 -> a3; h7: a4 -> a3; h8: a5 -> a4; h9: a3 -> a4; h10: a4 -> a5; h11: a6 -> a5; h12: a1 -> a6; h13: a5 -> a6; h14: a6 -> a1

L

L panel

K

K panel

R

R panel

Reaction Sketch

reaction sketch

Specified as a concerted guarded composite of primitive endpoint moves. Current HEG v2 lacks stereochemical/geometric guards, so this is a mechanism-design target.

Mechanism Flow

mechanism flow

Primitive Steps

first terminal diene-dienophile sigma bond forms

concerted pair cycle: pi(diene terminus) + pi(dienophile) -> sigma(C1,C6)

requires s-cis diene and dienophile pi resource

second terminal diene-dienophile sigma bond forms

concerted pair cycle: pi(diene terminus) + pi(dienophile) -> sigma(C4,C5)

requires no pre-existing terminal-dienophile bonds

internal diene pi bond shifts to cyclohexene pi bond

concerted pair cycle: pi(C2,C3) -> pi(cyclohexene)

requires cyclic ordering and admissible valence after composite

Guards and Alternatives

Guards

  • diene must be in s-cis topology.
  • dienophile must provide pi resource.
  • new sigma bonds must be absent before application.
  • regio- and stereochemical constraints are not yet represented by current labels.

Route probes

  • endo/exo and regioisomeric paths are genuine alternatives, but need geometry/stereochemistry metadata.
  • Without those guards a graph-only expansion would overgenerate.

Files